{"Equipment":"
Methods and procedures used not including center-specific data entry methods.
1. Sacrifice the mouse
2. Weigh and record total body weight
3. Place mouse on its back and pin the mouse onto board with extended extremities (inner side of hands and foot)
4. Wipe or wet the mouse with 70% ethanol to control hair and dander
5. Option A (for mice that are undergoing complete necropsy):
6. Option B (for mice that are not undergoing complete necropsy):
\n\tTo evaluate cardiac size using heart weight and body weight.
\n","Experimental Design":" \n\n\t
\n","Notes":"\n\t
\n\n\tAll data are collected at a local workstation in the necropsy room (attached to a digital balance) and uploaded to the Centre-specific pathology data capture system.
\n\n\tData QC
\n\t
\n\tMouse weight between 5 grams and 150 grams
\n\tIMPC Parameters (+ontology annotations)
\n\t
\n\tWeight (in mg)
\n\tData Analysis, annotation and display (+statistics)
\n\n\tStatistics: ANOVA/Wilcoxon test using normalized heart weights (for body weight) displayed in boxplot
\n"}